DSM-IV-TR (published in 2000) contains diagonostic criteria for 17 major catogories of mental disorders, comprising 375 discrete illnesses. It is used to diagonose mental disorders.
Now recently DSM 5 is published to replace DSM-IV-TR
FOR DIAGONOSIS OF SCHIZOPHRENIA IN EARLIER USED DSM-IV-TR CLASSIFICATION FOLLOWING WERE REQUIRED
Criterion A symptoms are : 2 OR MORE THAN 2 REQUIRED
[C] Disorganised speech
[d] Grossly disorganised or catatonic behaviour
[e] Negative symptoms ( ie affective flattening, alogia, avolition)
NOTE : IF BIZZARE DELUSION OR AUDITORY HALLUCINATION OF RUNNING COMMENTRY IS PRESENT ONY ONE CRITERIA IS SUFFICIENT( THIS POINT WAS REMOVED IN RECENT DSM 5 diagonostic criteria )
Highlights of Changes from DSM-IV-TR to DSM-5 IN RELATION TO DIAGONOSIS OF SCHIZOPHRENIA
Two changes were made to DSM-IV Criterion A for schizophrenia in recent DSM 5
 The first change is the elimination of the special attribution of bizarre delusions and Schneiderian first-rank auditory hallucinations (e.g., two or more voices conversing). In DSM-IV, only one such symptom was needed to meet the diagnostic requirement for Criterion A, instead of two of the other listed symptoms. Therefore, in DSM-5, two Criterion A symptoms are required for any diagnosis of schizophrenia.
 The second change is the addition of a requirement in Criterion A that the individual must have at least one of these three symptoms: delusions, hallucinations, and disorganized speech. At least one of these core “positive symptoms” is necessary for a reliable diagnosis of schizophrenia.
Changes made in Schizophrenia subtypes:-
In DSM 5 the DSM-IV subtypes of schizophrenia (i.e., paranoid, disorganized, catatonic, undifferentiated, and residual types) are eliminated due to their limited diagnostic stability, low reliability, and poor validity. These subtypes also have not been shown to exhibit distinctive patterns of treatment response or longitudinal course. Instead, a dimensional approach to rating severity for the core symptoms of schizophrenia is included.
QUICK REVISION OF SOME IMPORTANT POINTS OF SCHIZHOPHRENIA
**EMIL KRAEPLIN COINED THE TERM DEMENTIA PRAECOX(AI 2008).
*EUGENE BLEULER COINED THE TERM SCHIZOPHRENIA.
*INCIDENCE OF SCHIZOPHRENIA IS 1 – 1.5 % (TN 1999).SCHIZOPHRENIC SYMPTOMS RESULT FROM INCREASED LIMBIC DOPAMINERGIC ACTIVITY(IN MESOCORTICAL PATHWAY ) and NEGETIVE SYMPTOMS RESULT FROM DECREASED DOPAMINERGIC ACTIVITY IN FRONTAL CORTEX (PGI 97, 2002).
*PARANOID SCHIZOPHRENIA MAY BE CAUSED BY AMPHETAMINE INGESTION (AIIMS 90,97 MP 98).
*SCHIZOPHRENIA IS A FORMAL THOUGHT DISORDER ( AIIMS 94) ie primary disturbence în schizophrenia is THOUGHT DISTURBENCE
*MOST COMMON TYPE OF SCHIZOPHRENIA IS PARANOID SCHIZOPHRENIA(PGI 2004).
*PARANOID SCHIZOPRPHRENICS USULLY HAVE PREDOMINENT FIRST TWO OF SIGNS AND SYMPTOMS ie HALLUCINATION AND DELUSION.( remember russell crowe in the ” a beautiful mind” ) .
***CHARECTERISTIC / PATHOGNOMONIC CLINICAL MANISFESTATION OF SCHIZO IS AUDITORY HALLUCINATIONS GIVING RUNNING COMMENTRY ( AIIMS 2000, DELHI 03, PGI 98).
*AUDITORY HALLUCINATION ARE MOST COMMON TYPE OF HALLUCINATION IN SCHIZOPHRENICS ( JIPMER 95) and IT IS FIRST SYMPTOM TO GO AWAY /RESPOND TO TREATMENT ( AIIMS 92 , 93 , 90).
*DELUSION OF CONTROL ,PERSECUTION AND SELF REFERENCE ARE SEEN IN PARANOID SCHIZO( PGI 97).
**NOTE THAT DISORGANISED SPEECH , BEHAVIOUR AND NEGETIVE SYMPTOMS ARE NOT PROMINENT IN PARANOID SCHIZOPHRENIA.
*IT SHOWS SECOND BEST PROGONOSIS AMONG TYPES OF SCHIZO [ BEST PROGONOSIS IS WITH CATATONIC TYPE (MP 04) ].